Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373806 | 0.87 | — | — | |
| Iodide SCHEMBL6960852 | 0.85 | GSK3B (0.55) | GSK3BBCAT2POLBPKMNPC1 | |
| Iodide SCHEMBL6962185 | 0.85 | GSK3B (0.55) | GSK3BBCAT2POLBPKMNPC1 | |
| Trifluoroacetic Acid SCHEMBL7755164 | 0.78 | GSK3B (0.39) | GSK3BPOLBSLC6A1PKMNPC1 | |
| SCHEMBL30443444 | 0.77 | BCAT2 (0.53) | GSK3BBCAT2POLBPKMNPC1 | |
| SCHEMBL159280 | 0.73 | — | — | |
| SCHEMBL8710088 | 0.72 | NPC1 (0.47) | GSK3BPOLBPKMNPC1RAB9A | |
| SCHEMBL1291053 | 0.71 | ALDH1A1 (0.46) | BCAT2MAPTHPGDKMT2AGAA | |
| SCHEMBL10862218 | 0.71 | GSK3B (0.57) | GSK3BPOLBPKMNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3044528 | 0.71 | GSK3B (0.57) | GSK3BPOLBPKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309701-B2 | Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-12-18 | — | — | US | disclosed |