Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657121 | 0.90 | MEN1 (0.43) | CNR2POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5657720 | 0.88 | KDM4E (0.46) | SMN1; SMN2GPR55CNR2L3MBTL1PLA2G2A | |
| SCHEMBL5657737 | 0.87 | PDE4B (0.46) | SMN1; SMN2L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL5668947 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL5660910 | 0.81 | GPR55 (0.46) | SMN1; SMN2GPR55CNR1CNR2L3MBTL1 | |
| SCHEMBL5659886 | 0.81 | GPR55 (0.46) | SMN1; SMN2GPR55CNR1CNR2POLB | |
| SCHEMBL5658621 | 0.80 | KDM4E (0.49) | L3MBTL1POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5655678 | 0.80 | KMT2A (0.49) | SMN1; SMN2L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL5655596 | 0.79 | KDM4E (0.48) | L3MBTL1POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5659291 | 0.78 | MEN1 (0.41) | POLBKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030130-B2 | Benzofuran derivatives and their use as antibacterial agents | ARPIDA AG (CH) | 2006-04-18 | — | — | US | disclosed |
| EP-1307445-B1 | BENZOFURAN DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ARPIDA AG (CH) | 2005-12-21 | — | — | EP | disclosed |
| US-20040034047-A1 | Benzofuran derivatives and their use as antibacterial agents | EVOLVA SA (CH) | 2004-02-19 | — | — | US | disclosed |
| EP-1307445-A1 | BENZOFURAN DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Arpida AG, (CH) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010157-A1 | BENZOFURAN DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ARPIDA AG (CH) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034047-A1 | Benzofuran derivatives and their use as antibacterial agents | SBDS, BPTF, DCXR | SMN1; SMN2 3686/4885GPR55 3279/4885CNR1 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.