SCHEMBL5659751

SCHEMBL5659751

CC(C)(Oc1ccc(CCCCn2ccc3cc(OS(C)(=O)=O)ccc32)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 16/20 0.49
▸ PPARA Q07869 13/20 0.49
▸ PPARD Q03181 2/20 0.49
▸ PLA2G4A P47712 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5660741 0.97 PPARG (0.49) PPARGPPARAPPARD
SCHEMBL5660099 0.89 PPARA (0.43) PPARGPPARAPPARDPLA2G4A
SCHEMBL5659263 0.88 PPARG (0.54) PPARGPPARAPPARD
SCHEMBL5659260 0.88 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL5661074 0.87 PPARG (0.44) PPARGPPARAPPARDPLA2G4A
SCHEMBL5658238 0.87 PPARG (0.44) PPARGPPARAPPARDPLA2G4A
SCHEMBL5661012 0.86 PPARA (0.42) PPARGPPARAPPARDPLA2G4A
SCHEMBL14548504 0.85 PLA2G4A (0.39) PPARGPPARAPPARDPLA2G4A
Magnesium SCHEMBL5659480 0.85 PPARG (0.43) PPARGPPARAPPARDPLA2G4A
SCHEMBL5662947 0.85 PPARG (0.46) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070093476-A1 Novel compounds and their use in medicine,as antidiabetic and hypolipidemic agents, process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2007-04-26 — — US claimed
US-20070093476-A1 Novel compounds and their use in medicine,as antidiabetic and hypolipidemic agents, process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2007-04-26 — — US disclosed
US-20070093476-A1 Novel compounds and their use in medicine,as antidiabetic and hypolipidemic agents, process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2007-04-26 — — US disclosed
US-20070093476-A1 Novel compounds and their use in medicine,as antidiabetic and hypolipidemic agents, process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2007-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093476-A1 Novel compounds and their use in medicine,as antidiabetic and hypolipidemic agents, process for their preparation and pharmaceutical compositions containing them GPR119, NR1H3, NR1H2 PPARG 170/4885PPARA 251/4885PPARD 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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