Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658844 | 0.83 | CXCR1 (0.53) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5660811 | 0.80 | GAA (0.60) | MAPTALDH1A1SMN1; SMN2P4HTMKMT2A | |
| SCHEMBL3836094 | 0.78 | MAPT (0.76) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL11316237 | 0.75 | MAPT (0.76) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL5660133 | 0.74 | NOTUM (0.67) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL855050 | 0.74 | MAPT (0.66) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL12167759 | 0.73 | MAPT (0.73) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL5418542 | 0.73 | MAPT (0.73) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL11318162 | 0.73 | MAPT (0.73) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL9018657 | 0.73 | MEN1 (0.71) | MAPTALDH1A1POLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |