SCHEMBL566018

SCHEMBL566018

C1=CCC([Zr]c2cccc3c2Cc2ccccc2-3)=C1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
PGR P06401 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28768619 0.97 PNMT (0.38) PNMTNPC1RAB9AHTR7HTR2B
Butane SCHEMBL7928013 0.95 PNMT (0.39) PNMTNPC1RAB9AHTR7HTR2B
Diphenylmethane SCHEMBL28973332 0.90 PNMT (0.36) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6910606 0.83 PNMT (0.38) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30343000 0.81 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL4611115 0.81 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8163929 0.80 CA1 (0.36) NPC1RAB9ACA1CA2CA4
Methane SCHEMBL5839042 0.79 PNMT (0.50) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8733464 0.74 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3682618 0.74 PNMT (0.35) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705851-B9 Catalyst systems and process for producing broad molecular weight distribution polyolefin CONOCOPHILLIPS CO (US) 2004-08-11 EP claimed
EP-0705851-B1 Catalyst systems and process for producing broad molecular weight distribution polyolefin CONOCOPHILLIPS CO (US) 2004-01-21 EP claimed
EP-0659773-B1 Production of polyolefins containing long chain branches by a gas phase process UNION CARBIDE CHEM PLASTIC (US) 1998-08-19 EP claimed
CN-104744522-A Benzhydryl bridged cyclopentadienyl-fluorenyl zirconium compound and preparation method and applications thereof SHANGHAI NACO LUBRICATION COMPANY LTD 2015-07-01 CN disclosed
CN-104744522-A Benzhydryl bridged cyclopentadienyl-fluorenyl zirconium compound and preparation method and applications thereof SHANGHAI NACO LUBRICATION COMPANY LTD 2015-07-01 CN disclosed
EP-2663400-A1 PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF W. R. Grace & Co.-Conn (US) 2013-11-20 EP disclosed
US-8507608-B2 Propylene polymer resin composition TOSOH CORPORATION (JP) 2013-08-13 US disclosed
EP-2623560-A1 RESIN COMPOSITION FOR INJECTION MOLDING, INJECTION MOLDED FOAM ARTICLE, AND METHOD FOR PRODUCING INJECTION MOLDED FOAM ARTICLE Tosoh Corporation (JP) 2013-08-07 EP disclosed
US-20130189512-A1 RESIN COMPOSITION FOR INJECTION MOLDING, INJECTION MOLDED FOAM ARTICLE, AND METHOD FOR PRODUCING INJECTION MOLDED FOAM ARTICLE TOSOH CORPORATION (JP) 2013-07-25 US disclosed
EP-2420537-B1 PROPYLENE POLYMER RESIN COMPOSITION TOSOH CORP (JP) 2013-06-05 EP disclosed
WO-2012097146-A1 PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF W. R. GRACE & CO.-CONN. (US) 2012-07-19 WO disclosed
CN-1521194-A Transition metal catalyst component, aromatic vinyl compound polymer and method for its preparation ��Ԩ��ѧ��ҵ��ʽ���� 2004-08-18 CN disclosed
CN-1146596-C Transition metal catalyst component, aromatic vinyl compound polymer thereof and process for producing the same ��Ԩ��ѧ��ҵ��ʽ���� 2004-04-21 CN disclosed
US-6468936-B1 MIXTURE OF AN ALUMINOXANE AND A METALLOCENE; REDUCES REACTOR FOULING AND GIVES A POLYMER HAVING HIGH BULK DENSITY; EFFECTIVE FOR BOTH ISOSPECIFIC AND SYNDIOSPECIFIC POLYMERIZATION FINA TECHNOLOGY, INC. 2002-10-22 US disclosed
US-6444763-B1 Polymerization of olefins MITSUBISHI CHEMICAL CORPORATION (JP) 2002-09-03 US disclosed
EP-0874006-B1 Phyllosilicate-supported catalyst for the polymerisation of olefins MITSUBISHI CHEM CORP (JP) 2001-08-08 EP disclosed
WO-2000069959-A2 POLYMER LAYERED INORGANIC NANOCOMPOSITES NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY (US) 2000-11-23 WO disclosed
US-6048817-A Polymerization of olefins MITSUBISHI CHEMICAL CORPORATION (JP) 2000-04-11 US disclosed
EP-0874006-A1 Polymerisation of olefins MITSUBISHI CHEMICAL CORPORATION (JP) 1998-10-28 EP disclosed
CN-1196357-A Transition metal catalyst component, aromatic vinyl compound polymer thereof and process for producing the same DENKI KAGAKU KOGYO KK (JP) 1998-10-21 CN disclosed