Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611115 | 0.89 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30343000 | 0.89 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Methane SCHEMBL5839042 | 0.87 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL524602 | 0.76 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30103334 | 0.76 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL566018 | 0.74 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL2877998 | 0.74 | PNMT (0.61) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8416843 | 0.74 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| Water SCHEMBL27894037 | 0.72 | PNMT (0.50) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL22263591 | 0.71 | PNMT (0.57) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748821-B1 | Transition metal compound | TARGOR GMBH (DE) | 1998-11-04 | — | — | EP | disclosed |
| EP-0748821-A1 | Transition metal compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |