SCHEMBL566090

SCHEMBL566090

Oc1ccc(-c2ccc(I)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.69
ESR2 Q92731 3/20 0.69
MMP3 P08254 2/20 0.55
BCL2L1 Q07817 1/20 0.55
ABL1 P00519 1/20 0.52
ABCB1 P08183 1/20 0.52
BCR P11274 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
NFKB1 P19838 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CA12 O43570 1/20 0.50
GMNN O75496 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10715675 0.90 ALOX15 (0.61) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL27309628 0.90 ALOX15 (0.61) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL5514 0.90
SCHEMBL27567995 0.87
Ammonia Solution, Strong SCHEMBL27957961 0.87
SCHEMBL11575593 0.87
Benzene SCHEMBL9823128 0.84 CA12 (0.53) ESR1ESR2MMP3BCL2L1MEN1
Ethylene SCHEMBL27784145 0.84 HSD17B10 (0.53) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL6292004 0.83 ESR1 (1.00) ESR1ESR2MMP3BCL2L1ABL1
Hydroquinone SCHEMBL5712110 0.83 ESR1 (1.00) ESR1ESR2MMP3BCL2L1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113156137-A Chemiluminescence immunoassay kit for detecting CD47, and preparation method and application thereof 山东省大健康精准医疗产业技术研究院 2021-07-23 CN claimed
JP-4099754-A None JP disclosed
CN-118858262-B High-sensitivity single-component chemiluminescent substrate, long-acting storage container and application thereof 上海碧云天生物技术股份有限公司 2025-04-22 CN disclosed
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) 2024-12-26 US disclosed
EP-3808747-B1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL (JP) 2024-12-18 EP disclosed
CN-118858262-A High-sensitivity single-component chemiluminescent substrate, long-acting storage container and application thereof 上海碧云天生物技术股份有限公司 2024-10-29 CN disclosed
US-12077531-B2 Imidazopyridinone compound KISSEI PHARMACEUTICAL CO., LTD. (JP) 2024-09-03 US disclosed
CN-112689637-B Imidazopyridone compounds 橘生药品工业株式会社 2023-11-10 CN disclosed
CN-111205344-B Pure organic phosphorescent small-molecule material for methanol solvent recognition and preparation method thereof 华东理工大学 2023-03-14 CN disclosed
CN-113841085-A Polymer composition, liquid crystal alignment film, liquid crystal display element, and method for producing substrate having liquid crystal alignment film 日产化学株式会社 2021-12-24 CN disclosed
EP-1038939-A1 CHEMILUMINESCENT REAGENTS AND CHEMILUMINESCENCE ANALYSIS METHODS WITH THE USE OF THE SAME DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2000-09-27 EP disclosed
US-5985853-A β-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides HOECHST MARION ROUSSEL (FR) 1999-11-16 US disclosed
US-5319069-A Catalyzing a di-iodoaryl-diethylene glycol with a dimethyl diphenylamines in presence of copper particle, copper oxide or copper halogenide to form di-tertaminearyl diethylene glycol RICOH COMPANY, LTD. (JP) 1994-06-07 US disclosed
EP-0390945-B1 Process for preparing 4,4'''-dihydroxyquater-phenyl or derivatives thereof SANKO KAIHATSU KAGAKU KENK (JP) 1993-11-18 EP disclosed
US-5248826-A Electrophotographic photoconductor with electroconductive supports and a photoconductive layers with charge transport compounds RICOH COMPANY, LTD. (JP) 1993-09-28 US disclosed
US-5158850-A Polyether compounds and electrophotographic photoconductor comprising one polyether compound RICOH COMPANY, LTD. (JP) 1992-10-27 US disclosed
JP-H0499754-A TOLAN-BASED COMPOUND AND CHIRAL SMECTIC LIQUID CRYSTAL COMPOSITION USING THE SAME COMPOUND KANEBO LTD 1992-03-31 JP disclosed
EP-0390945-A1 Process for preparing 4,4'''-dihydroxyquater-phenyl or derivatives thereof Sanko Kaihatsu Kagaku Kenkyusho (JP) 1990-10-10 EP disclosed
EP-0102719-A1 Wholly aromatic polyesters comprising 6-oxy-2-naphthoyl moiety and 4-oxy-4'-carboxy biphenyl moiety CELANESE CORPORATION (US) 1984-03-14 EP disclosed
US-4431770-A Wholly aromatic polyester comprising 4-oxy-4'-carboxybiphenyl moiety which is capable of forming an anisotropic melt phase CELANESE CORPORATION (US) 1984-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077531-B2 Imidazopyridinone compound EGLN3, DHPS, EGLN2 ESR1 3694/4885ESR2 3465/4885MMP3 262/4885
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND EGLN3, DHPS, EGLN2 ESR1 3694/4885ESR2 3465/4885MMP3 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.