SCHEMBL5662971

SCHEMBL5662971

Fc1ccc(C=CC=Cc2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.48
HSD11B1 P28845 1/20 0.43
APP P05067 3/20 0.42
PTGS1 P23219 1/20 0.42
FBP1 P09467 1/20 0.41
TNFRSF1A P19438 1/20 0.39
MAOB P27338 1/20 0.39
NQO2 P16083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9970468 0.93 APP (0.44) NFE2L2HSD11B1APPPTGS1MAOB
SCHEMBL9970459 0.85 NFE2L2 (0.62) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL13790314 0.83 NFE2L2 (0.61) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL13790298 0.78 NFE2L2 (0.46) NFE2L2APPPTGS1
SCHEMBL13790300 0.78 NFE2L2 (0.46) NFE2L2APPPTGS1
SCHEMBL29190717 0.74 NFE2L2 (0.50) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL700051 0.74 NFE2L2 (0.78) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL22468800 0.74 NFE2L2 (0.78) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL13766470 0.74 NFE2L2 (0.78) NFE2L2HSD11B1APPPTGS1FBP1
SCHEMBL700052 0.74 NFE2L2 (0.78) NFE2L2HSD11B1APPPTGS1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1397260-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2006-03-08 EP disclosed
EP-1397260-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2004-03-17 EP disclosed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO disclosed