SCHEMBL9970468

SCHEMBL9970468

Fc1c(F)c(F)c(/C=C/C=C/c2ccc(/C=C/C=C/c3c(F)c(F)c(F)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.44
MAOB P27338 1/20 0.43
NFE2L2 Q16236 5/20 0.37
ALDH1A1 P00352 2/20 0.34
VCP P55072 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
HSD11B1 P28845 1/20 0.33
PTGS1 P23219 1/20 0.32
TRPA1 O75762 1/20 0.32
LMNA P02545 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5662971 0.93 NFE2L2 (0.48) APPMAOBNFE2L2HSD11B1PTGS1
SCHEMBL13790298 0.83 NFE2L2 (0.46) APPNFE2L2VCPPTGS1
SCHEMBL13790300 0.83 NFE2L2 (0.46) APPNFE2L2VCPPTGS1
SCHEMBL9970459 0.75 NFE2L2 (0.62) APPMAOBNFE2L2HSD11B1PTGS1
SCHEMBL13790314 0.74 NFE2L2 (0.61) APPNFE2L2HSD11B1PTGS1ALOX5
SCHEMBL4159222 0.72 NFE2L2 (0.64) MAOBNFE2L2ALDH1A1TRPA1LMNA
SCHEMBL4155482 0.72 NFE2L2 (0.64) MAOBNFE2L2ALDH1A1TRPA1LMNA
SCHEMBL813058 0.72 NFE2L2 (0.64) MAOBNFE2L2ALDH1A1TRPA1LMNA
SCHEMBL10037363 0.72 FFAR1 (0.40) APPNFE2L2PTGS1
SCHEMBL10031872 0.72 NFE2L2 (0.45) NFE2L2KDM4EPTGS1TRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203139-B2 Organic thin film transistor and organic thin film light-emitting transistor using an organic semiconductor layer having an aromatic hydrocarbon group or an aromatic heterocyclic group in the center thereof IDEMITSU KOSAN CO., LTD (JP) 2012-06-19 US disclosed
US-8203139-B2 Organic thin film transistor and organic thin film light-emitting transistor using an organic semiconductor layer having an aromatic hydrocarbon group or an aromatic heterocyclic group in the center thereof IDEMITSU KOSAN CO., LTD (JP) 2012-06-19 US disclosed
US-20100051919-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-03-04 US disclosed
US-20100051919-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-03-04 US disclosed