SCHEMBL5662977

SCHEMBL5662977

C=Cc1ccc(C(C)c2cccc(C(C)c3ccccc3C=C)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
TYR P14679 1/20 0.33
PTGS2 P35354 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC6A4 P31645 1/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5070661 0.92 ALDH1A1 (0.39) ALDH1A1TSHRTYRPTGS2
SCHEMBL5662269 0.91 PTGS2 (0.39) ALDH1A1TSHRTYRPTGS2TP53
SCHEMBL5070695 0.90 TP53 (0.40) ALDH1A1TSHRTYRPTGS2TP53
SCHEMBL5664305 0.89 ALDH1A1 (0.36) ALDH1A1TYRTP53TDP1SLC6A4
SCHEMBL5135462 0.88 ALDH1A1 (0.38) ALDH1A1TSHRTYRPTGS2EGFR
SCHEMBL1646805 0.86 ALDH1A1 (0.44) ALDH1A1TSHRTYRPTGS2TP53
SCHEMBL5663673 0.84 ALDH1A1 (0.40) ALDH1A1TSHRTYRSLC6A4
SCHEMBL5070673 0.84 TP53 (0.40) ALDH1A1TSHRTYRPTGS2TP53
SCHEMBL5662398 0.83 TP53 (0.42) ALDH1A1TSHRTYRPTGS2TP53
SCHEMBL5073357 0.82 TYR (0.42) ALDH1A1TSHRTYRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070144972-A1 Monolithic Organic Copolymer for Biopolymer Chromatography LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) 2007-06-28 US disclosed