Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.74 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | GAPDH | P04406 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664510 | 1.00 | ENPP1 (0.74) | ENPP1P2RX3P2RX4P2RX2ADORA3 | |
| SCHEMBL5797743 | 0.89 | P2RX3 (0.66) | ENPP1P2RX3P2RX4P2RX2ADORA3 | |
| SCHEMBL13046091 | 0.89 | P2RX3 (0.66) | ENPP1P2RX3P2RX4P2RX2ADORA3 | |
| SCHEMBL5797749 | 0.89 | P2RX3 (0.66) | ENPP1P2RX3P2RX4P2RX2ADORA3 | |
| SCHEMBL532929 | 0.88 | ENPP1 (0.71) | ENPP1P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL5983100 | 0.88 | ENPP1 (0.71) | ENPP1P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL5794949 | 0.88 | ENPP1 (0.71) | ENPP1P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL532930 | 0.88 | ENPP1 (0.71) | ENPP1P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL29810828 | 0.86 | ENPP1 (0.99) | ENPP1P2RX3P2RX4P2RX2SMN1; SMN2 | |
| SCHEMBL6268270 | 0.86 | TYMP (0.57) | ENPP1P2RX3P2RX4P2RX2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006014055-A1 | METHODS FOR INTERLEUKIN-10 EXPRESSION IN MICROGLIAL CELLS | AJOU UNIVERSITY INDUSTRY COOPERATION FOUNDATION (KR) | 2006-02-09 | — | — | WO | disclosed |