Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.66 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.66 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.66 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.66 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.66 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.66 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.66 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797743 | 1.00 | P2RX3 (0.66) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5797749 | 1.00 | P2RX3 (0.66) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5794860 | 0.90 | ADORA1 (0.61) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5664518 | 0.89 | ENPP1 (0.74) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5664510 | 0.89 | ENPP1 (0.74) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5793980 | 0.89 | ADORA1 (0.64) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL5793976 | 0.89 | ADORA1 (0.64) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL29187216 | 0.86 | ADORA1 (0.73) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL22571191 | 0.86 | P2RX3 (0.64) | P2RX3P2RX4P2RX2P2RY11P2RX6 | |
| SCHEMBL29479253 | 0.86 | LMNA (0.57) | ADORA1ADORA3MAPK1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238139-B1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-09-27 | — | — | EP | disclosed |
| US-20150238640-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-08-27 | — | — | US | disclosed |
| US-20150238640-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-08-27 | — | — | US | disclosed |
| US-20100290990-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | BARRE LOUISA | 2010-11-18 | — | — | US | disclosed |
| US-20100290990-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | BARRE LOUISA | 2010-11-18 | — | — | US | disclosed |
| WO-2009087066-A2 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238640-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | TPMT, NUDT1, DUT | P2RX3 135/4885P2RX4 131/4885P2RX2 132/4885 |
| US-20100290990-A1 | METHOD FOR PREPARING A MARKED PURINE DERIVATIVE, SAID DERIVATIVE AND USES THEREOF | TPMT, NUDT1, DUT | P2RX3 135/4885P2RX4 131/4885P2RX2 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.