Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746787 | 1.00 | MEN1 (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11314459 | 0.93 | KMT2A (0.39) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL6293211 | 0.87 | SLC6A4 (0.36) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Bromide SCHEMBL6293220 | 0.86 | SLC6A4 (0.35) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6294511 | 0.80 | HTR1A (0.35) | MEN1KMT2ALMNAMAPK1NPSR1 | |
| SCHEMBL6298575 | 0.80 | SLC6A4 (0.32) | MEN1KMT2ALMNAMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL6297623 | 0.79 | HTR1A (0.35) | MEN1KMT2ALMNAMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL6294439 | 0.79 | MEN1 (0.33) | MEN1KMT2ALMNAMAPK1NPSR1 | |
| Iodide SCHEMBL31409454 | 0.79 | SLC6A4 (0.34) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8430267 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPK1NPSR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601382-A4 | PHOSPHOLIPID SCRAMBLASE 3 | UNIV UTAH RES FOUND (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20060172958-A1 | Phospholipid scramblase 3 | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2006-08-03 | — | — | US | disclosed |
| EP-1601382-A2 | PHOSPHOLIPID SCRAMBLASE 3 | University of Utah Research Foundation (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004081200-A2 | PHOSPHOLIPID SCRAMBLASE 3 | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2004-09-23 | — | — | WO | disclosed |