Oxirane

Oxirane

SCHEMBL5664684

C1CO1.C=C(C)C(=O)OCCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.44
POLB P06746 2/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
ACHE P22303 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15480 0.90 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
Oxirane SCHEMBL170556 0.89 THRB (0.50) TSHRTHRBALDH1A1POLBAPEX1
Lithium SCHEMBL31087663 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
Ammonia Solution, Strong SCHEMBL28569838 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28378579 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
Potassium SCHEMBL31087662 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
Water SCHEMBL7119412 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL8398425 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28973888 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL31250004 0.88 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383656-A4 METALLIZED INKJET SUBSTRATES AND METHODS OF MAKING THE SAME AVERY DENNISON CORP (US) 2006-07-19 EP disclosed
EP-1383656-A1 METALLIZED INKJET SUBSTRATES AND METHODS OF MAKING THE SAME AVERY DENNISON CORPORATION (US) 2004-01-28 EP disclosed
WO-2002083426-A1 METALLIZED INKJET SUBSTRATES AND METHODS OF MAKING THE SAME AVERY DENNISON CORPORATION (US) 2002-10-24 WO disclosed