Oxirane

Oxirane

SCHEMBL170556

C1CO1.C=C(C)C(=O)OCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 5/20 0.48
ALDH1A1 P00352 2/20 0.47
POLB P06746 2/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL158462 0.98 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL27539985 0.94 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14648232 0.94 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
Tetrahydrofuran SCHEMBL5508826 0.91 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
Oxirane SCHEMBL3776781 0.90 THRB (0.61) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL29229747 0.89 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14886 0.89
SCHEMBL6864388 0.89 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9419658 0.89 TSHR (0.47) THRBTSHRALDH1A1POLBAPEX1
Oxirane SCHEMBL5664684 0.89 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427513-B1 INTERPENETRATING NETWORK OF ANION-EXCHANGE POLYMERS, PRODUCTION METHOD THEREOF AND USE OF SAME Electricité de France (FR) 2016-02-10 EP claimed
US-9136550-B2 Interpenetrating network of anion-exchange polymers, production method thereof and use of same ELECTRICITE DE FRANCE (FR) 2015-09-15 US claimed
US-20140343222-A1 POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF SEGETIS, INC (US) 2014-11-20 US claimed
EP-2776491-A1 POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF Segetis, Inc. (US) 2014-09-17 EP claimed
WO-2013071256-A1 POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF SEGETIS, INC. (US) 2013-05-16 WO claimed
US-20120118832-A1 IONIC POLYMERS, METHOD OF MANUFACTURE, AND USES THEREOF SEGETIS, INC. (US) 2012-05-17 US claimed
US-20120058413-A1 INTERPENETRATING NETWORK OF ANION-EXCHANGE POLYMERS, PRODUCTION METHOD THEREOF AND USE OF SAME UNIVERSITE DE CERGY PONTOISE (FR) 2012-03-08 US claimed
US-9911999-B2 Interpenetrating network of anion-exchange polymers, production method thereof and use of same ELECTRICITE DE FRANCE (FR) 2018-03-06 US disclosed
US-20160049679-A1 Interpenetrating Network of Anion-Exchange Polymers, Production Method Thereof and Use of Same ELECTRICITE DE FRANCE (FR) 2016-02-18 US disclosed
US-9136550-B2 Interpenetrating network of anion-exchange polymers, production method thereof and use of same ELECTRICITE DE FRANCE (FR) 2015-09-15 US disclosed
US-20130261254-A1 REACTIVE DILUENTS, METHODS OF REACTING, AND THERMOSET POLYMERS DERIVED THEREFROM SEGETIS, INC. (US) 2013-10-03 US disclosed
WO-2013148933-A1 REACTIVE DILUENTS, METHODS OF REACTING, AND THERMOSET POLYMERS DERIVED THEREFROM SEGETIS, INC. (US) 2013-10-03 WO disclosed
EP-2287270-B1 Compound containing a fluorinated amide group DU PONT (US) 2013-04-03 EP disclosed
US-20080039605-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. DU PONT DE NEMOURS AND COMPANY 2008-02-14 US disclosed
EP-1177830-B1 Reaction method using heterogeneous catalyst and reaction apparatus therefor NIPPON CATALYTIC CHEM IND (JP) 2007-07-18 EP disclosed
WO-2007035936-A2 TRIAZOLE-CONTAINING FLUORINATED POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-29 WO disclosed
US-20070066762-A1 Triazole-containing fluorinated polymers E. I. DU PONT DE NEMOURS AND COMPANY 2007-03-22 US disclosed
US-20070066767-A1 Polyalkylene glycols NIPPON SHOKUBAI CO., LTD. (JP) 2007-03-22 US disclosed
EP-1177830-A2 Reaction method using heterogeneous catalyst and reaction apparatus therefor Nippon Shokubai Co., Ltd. (JP) 2002-02-06 EP disclosed
US-5362767-A Copolymers comprising propellanes and contact lenses made therefrom CIBA-GEIGY CORPORATION (US) 1994-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066767-A1 Polyalkylene glycols PUF60, PARG, DGAT1 THRB 4016/4885TSHR 2941/4885ALDH1A1 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.