Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664573 | 0.84 | ALDH1A1 (0.46) | RAB9ALMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL5663585 | 0.82 | KCNA5 (0.51) | RAB9ALMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL5664615 | 0.80 | KCNA5 (0.46) | HPGDRAB9ALMNAALDH1A1CYP3A4 | |
| SCHEMBL4204369 | 0.79 | HPGD (0.59) | HPGDRAB9ANPC1CA12CA9 | |
| SCHEMBL4192663 | 0.79 | HPGD (0.59) | HPGDRAB9ANPC1CA12CA9 | |
| SCHEMBL5666578 | 0.78 | KCNA5 (0.44) | RAB9ALMNAALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL27601234 | 0.78 | HPGD (0.58) | HPGDRAB9ANPC1CA12CA9 | |
| Hydrochloric Acid SCHEMBL4208519 | 0.78 | HPGD (0.58) | HPGDRAB9ANPC1CA12CA9 | |
| SCHEMBL5664800 | 0.78 | ALDH1A1 (0.48) | RAB9ALMNAALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL4203336 | 0.77 | HPGD (0.56) | HPGDRAB9ANPC1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716137-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080373-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |