Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134915 | 0.93 | KDR (0.43) | KDREGFRILKFGFR1FLT1 | |
| SCHEMBL5665202 | 0.84 | KDR (0.42) | KDREGFRILKFGFR1FLT1 | |
| SCHEMBL5664940 | 0.82 | KDR (0.43) | KDREGFRILKFGFR1FLT1 | |
| SCHEMBL5664809 | 0.81 | LDHA (0.40) | KDRKDM1ATDP2NSD2PAX8 | |
| SCHEMBL5134914 | 0.69 | KDR (0.55) | KDREGFR | |
| SCHEMBL5134656 | 0.68 | LDHA (0.42) | EGFRKDM1AKIT | |
| SCHEMBL23264581 | 0.67 | KDR (0.54) | KDREGFRILKFGFR1FLT1 | |
| SCHEMBL4512570 | 0.67 | KDR (0.57) | KDREGFRILKFGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL5566426 | 0.66 | KDR (0.56) | KDREGFRILKFGFR1FLT1 | |
| SCHEMBL180323 | 0.65 | EGFR (0.48) | KDREGFRILKFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | KDR 1/4885EGFR 439/4885ILK 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.