SCHEMBL5665167

SCHEMBL5665167

CCN(CC)c1ccc(C(c2ccc(N(CC)CC)cc2C)c2cccc3ccccc23)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
GAA P10253 2/20 0.49
PKM P14618 1/20 0.49
HTT P42858 1/20 0.49
MCL1 Q07820 1/20 0.49
S100B P04271 1/20 0.43
MEN1 O00255 2/20 0.40
NPC1 O15118 2/20 0.40
KMT2A Q03164 2/20 0.40
SLC2A1 P11166 1/20 0.38
HCRTR1 O43613 1/20 0.38
MAPK1 P28482 1/20 0.38
PLK1 P53350 1/20 0.38
S1PR1 P21453 1/20 0.37
ALDH1A1 P00352 3/20 0.37
TERT O14746 1/20 0.37
CYP3A4 P08684 1/20 0.37
GRK6 P43250 1/20 0.37
RAB9A P51151 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5554796 0.89 MEN1 (0.40) MAPTGAAPKMHTTMCL1
SCHEMBL5007884 0.84 GAA (0.43) MAPTGAAPKMHTTMCL1
SCHEMBL5670988 0.83 MAPT (0.46) MAPTGAAPKMHTTMCL1
SCHEMBL81551 0.83 S100B (0.58) MAPTGAAPKMHTTMCL1
SCHEMBL10478403 0.83 MAPT (0.43) MAPTGAAPKMHTTMCL1
Hydrochloric Acid SCHEMBL237984 0.82 S100B (0.56) MAPTGAAPKMHTTMCL1
Hydrochloric Acid SCHEMBL6373886 0.80 S100B (0.55) MAPTGAAPKMHTTMCL1
SCHEMBL5555787 0.80 MAPT (0.43) MAPTGAAPKMHTTMCL1
SCHEMBL80267 0.80 MAPT (0.73) MAPTGAAPKMHTTMCL1
SCHEMBL7952524 0.78 S100B (0.49) MAPTGAAPKMHTTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
WO-2005050757-A2 NANOTUBE-ORGANIC PHOTOELECTRIC CONVERSION DEVICES AND METHODS OF MAKING SAME RENSSELAER POLYTECHNIC INSTITUTE (US) 2005-06-02 WO disclosed
US-4818660-A POLYMERIC BINDER AND UNSATURATED COMPOUND, PHOTOINITIATOR, BAS IC DYE, LEUCO DYE AND STRONG ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US disclosed
US-4500623-A Photoconductive compositions comprising an organic photoconductor and a thioamide compound and electrophotographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4125414-A PHOTOCONDUCTIVE MATERIAL CONTAINS ELECTRICALLY INSULATING BINDER, A PYRYLIUM-TYPE DYE SALT, AND ORGANIC PHOTOCONDUCTOR EASTMAN KODAK COMPANY (US) 1978-11-14 US disclosed