Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 13/20 | 0.70 |
| ▸ | CCR1 | P32246 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CCR4 | P51679 | 2/20 | 0.61 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670223 | 0.86 | CCR2 (0.77) | CCR2CCR1MEN1KMT2ACYP1A2 | |
| SCHEMBL7348029 | 0.86 | MEN1 (0.70) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Diphenylmethanol SCHEMBL8077142 | 0.81 | CCR2 (0.68) | CCR2CCR1MEN1KMT2ACYP1A2 | |
| SCHEMBL5666146 | 0.79 | CCR2 (0.67) | CCR2CCR1MEN1KMT2ACYP1A2 | |
| SCHEMBL3563444 | 0.78 | SLC16A3 (0.74) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL1035847 | 0.78 | MEN1 (1.00) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7188482 | 0.77 | SLC16A3 (0.54) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL18151726 | 0.77 | KMT2A (0.67) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7208212 | 0.77 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL3554736 | 0.76 | SLC16A3 (0.68) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799198-B1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-08-30 | — | — | EP | claimed |
| EP-0799198-A4 | — | — | 1997-10-15 | — | — | EP | claimed |
| EP-0799198-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | claimed |
| WO-1995033461-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | claimed |
| EP-0904069-A4 | PLA2 INHIBITORS OF ANGIOGENESIS | SMITHKLINE BEECHAM CORP (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-0799198-B1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0904069-A1 | PLA2 INHIBITORS OF ANGIOGENESIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0799198-A4 | — | — | 1997-10-15 | — | — | EP | disclosed |
| EP-0799198-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1997035567-A1 | PLA2 INHIBITORS OF ANGIOGENESIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-02 | — | — | WO | disclosed |
| US-5545669-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORPORATION | 1996-08-13 | — | — | US | disclosed |
| WO-1995033461-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |