SCHEMBL5665371

SCHEMBL5665371

CCN(CC)c1ccc(C(c2ccc(N(CC)CC)cc2C)c2c(C)n(Cc3ccccc3)c3ccccc23)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
GRIA2 P42262 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP19A1 P11511 1/20 0.40
MAPT P10636 3/20 0.38
GAA P10253 2/20 0.38
PKM P14618 2/20 0.38
HTT P42858 1/20 0.38
MCL1 Q07820 1/20 0.38
PLA2G2A P14555 4/20 0.38
PLA2G10 O15496 1/20 0.38
NTRK1 P04629 1/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665378 0.91 KMT2A (0.43) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5666758 0.89 CYP19A1 (0.42) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5666766 0.80 CYP19A1 (0.42) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL7181782 0.77 MAPT (0.38) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL9659204 0.74 CYP19A1 (0.54) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL10478403 0.74 MAPT (0.43) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5011777 0.73 TSHR (0.56) KMT2AMAPK1ALDH1A1KDM4EGRIA2
SCHEMBL5664993 0.73 KDM4E (0.46) KMT2AMEN1SMN1; SMN2KDM4ETDP1
SCHEMBL12765062 0.72 ATM (0.36) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL133593 0.71 S100B (0.49) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed