SCHEMBL5665378

SCHEMBL5665378

CCN(CC)c1ccc(C)c(C(c2cc(N(CC)CC)ccc2C)c2c(C)n(Cc3ccccc3)c3ccccc23)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
GRIA2 P42262 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP19A1 P11511 1/20 0.40
PLA2G2A P14555 4/20 0.38
PLA2G10 O15496 1/20 0.38
NTRK1 P04629 1/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
P2RX4 Q99571 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665371 0.91 KMT2A (0.43) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5666766 0.89 CYP19A1 (0.42) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5666758 0.80 CYP19A1 (0.42) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL11267044 0.74 ALDH1A1 (0.33) SMN1; SMN2MAPK1ALDH1A1KDM4ETDP1
SCHEMBL9659204 0.74 CYP19A1 (0.54) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5665001 0.73 KDM4E (0.46) KMT2AMEN1SMN1; SMN2MAPK1KDM4E
SCHEMBL237533 0.71 S100B (0.45) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL81552 0.71 S100B (0.53) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL7181782 0.69 MAPT (0.38) KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1
SCHEMBL5554796 0.69 MEN1 (0.40) KMT2AMEN1MAPK1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed