Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518826 | 0.79 | TGFBR1 (0.46) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL799428 | 0.79 | TGFBR1 (0.37) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL17187716 | 0.77 | CYP2D6 (0.45) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL366427 | 0.76 | CYP2D6 (0.52) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL10750333 | 0.76 | ANPEP (0.36) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL491544 | 0.76 | TGFBR1 (0.35) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL442805 | 0.76 | HRH4 (0.37) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL3734949 | 0.74 | GAA (0.44) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL16097 | 0.74 | TGFBR1 (0.39) | TGFBR1RXFP1MEN1KMT2A | |
| SCHEMBL9289423 | 0.74 | TGFBR1 (0.39) | TGFBR1RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418013-A1 | CHARGE-MOSAIC MEMBRANE | Yamaguchi University (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-20120034481-A1 | CHARGE-MOSAIC MEMBRANE | KURARAY CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |