Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.50 |
| ▸ | GABRE | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL31157624 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4LMNACAMK2A | |
| Adipic Acid SCHEMBL6131152 | 1.00 | GPR84 (0.54) | GPR84FFAR1FFAR4LMNACAMK2A | |
| Azelaic Acid SCHEMBL28859389 | 0.98 | GPR84 (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Pimelic Acid SCHEMBL30288567 | 0.98 | GPR84 (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Sebacic Acid SCHEMBL25336327 | 0.98 | GPR84 (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Adipic Acid SCHEMBL28657332 | 0.96 | GPR84 (0.62) | GPR84FFAR1FFAR4LMNACAMK2A | |
| Glutarate SCHEMBL30288574 | 0.95 | SLC22A6 (0.52) | GPR84FFAR1FFAR4LMNACAMK2A | |
| SCHEMBL4478217 | 0.94 | GPR84 (0.54) | GPR84FFAR1FFAR4LMNATSHR | |
| SCHEMBL4476387 | 0.94 | GPR84 (0.54) | GPR84FFAR1FFAR4LMNATSHR | |
| SCHEMBL4470155 | 0.94 | GPR84 (0.54) | GPR84FFAR1FFAR4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946581-B | Single-component polyurethane primer and adhesive tape using same | 东莞澳中新材料科技股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4573141-A1 | THERMOPLASTIC POLYURETHANE MATERIALS HAVING GOOD ELASTIC RECOVERY AND LOW SOFTENING TEMPERATURE | Huntsman International LLC (US) | 2025-06-25 | — | — | EP | claimed |
| US-20240400859-A1 | PHOTOCURABLE POLYMERS AND COMPOSITIONS FOR 3D PRINTING RESINS | ALIGN TECHNOLOGY, INC. | 2024-12-05 | — | — | US | claimed |
| CN-116285847-B | High-adhesion reactive polyurethane hot melt adhesive and preparation method thereof | 烟台德邦科技股份有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118185549-A | Bio-based polyurethane adhesive for aluminum adhesion, and preparation method and application thereof | 华南理工大学 | 2024-06-14 | — | — | CN | claimed |
| CN-118063735-A | Wet polyurethane resin and preparation method and application thereof | 上海汇得科技股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117946581-A | Single-component polyurethane primer and adhesive tape using same | 东莞澳中新材料科技股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-113226642-B | Polishing pad | 株式会社可乐丽 | 2024-03-15 | — | — | CN | claimed |
| WO-2024038104-A1 | THERMOPLASTIC POLYURETHANE MATERIALS HAVING GOOD ELASTIC RECOVERY AND LOW SOFTENING TEMPERATURE | HUNTSMAN INTERNATIONAL LLC (US) | 2024-02-22 | — | — | WO | claimed |
| US-11725128-B2 | Impregnation sealant for electronic components | HENKEL AG & CO. KGAA (DE) | 2023-08-15 | — | — | US | claimed |
| CN-114163965-A | Bi-component solvent-free polyurethane adhesive for solar backboard | 沈阳化工研究院有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-113667392-A | UV (ultraviolet) light-cured resin for elastic veneer and preparation method thereof | 珠海展辰新材料股份有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-113226642-A | Polishing pad | 株式会社可乐丽 | 2021-08-06 | — | — | CN | claimed |
| CN-113166358-A | Process for preparing silane-modified polymers | 默兹奔特利股份公司 | 2021-07-23 | — | — | CN | claimed |
| CN-111533871-A | Composition for assisting in improving moisture permeability of polyurethane and polyurethane hot melt adhesive containing composition | 上海抚佳精细化工有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-111394028-A | Photo-activated delayed thermosetting adhesive and preparation method thereof | 枚林优交(上海)新材料开发有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111072913-A | Solvent-free polyurethane resin for automobile seat leather and preparation method thereof | 浙江禾欣科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| EP-2842979-A1 | POLYURETHANE FOAMING COMPOSITION AND METHOD FOR PRODUCING FLEXIBLE POLYURETHANE FOAM | Momentive Performance Materials Japan LLC (JP) | 2015-03-04 | — | — | EP | claimed |
| US-20150038604-A1 | EXPANDABLE POLYURETHANE COMPOSITION AND MANUFACTURING METHOD OF FLEXIBLE POLYURETHANE FOAM | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2015-02-05 | — | — | US | claimed |
| US-5242965-A | Heat resistant, compressive strength, tensile strength and wear resistance | CHISSO CORPORATION (JP) | 1993-09-07 | — | — | US | claimed |