Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487380 | 0.86 | AKR1C1 (0.47) | AKR1C1ALDH1A1LDHACHRM2CHRM4 | |
| SCHEMBL4637584 | 0.86 | AKR1C1 (0.47) | AKR1C1ALDH1A1LDHACHRM2CHRM4 | |
| SCHEMBL4637662 | 0.86 | AKR1C1 (0.47) | AKR1C1ALDH1A1LDHACHRM2CHRM4 | |
| SCHEMBL6326779 | 0.84 | LMNA (0.36) | AKR1C1ALDH1A1LMNAOPRM1OPRL1 | |
| Ammonia Solution, Strong SCHEMBL6650400 | 0.84 | AKR1C1 (0.45) | AKR1C1ALDH1A1LDHACHRM2CHRM4 | |
| SCHEMBL6435655 | 0.84 | AKR1C1 (0.39) | AKR1C1ALDH1A1LDHACHRM2CHRM4 | |
| SCHEMBL11609809 | 0.76 | NR4A1 (0.45) | ALDH1A1LMNAHTTNPSR1SMN1; SMN2 | |
| Potassium Ion SCHEMBL11295824 | 0.73 | AKR1C1 (0.38) | AKR1C1LDHALMNAOPRM1OPRL1 | |
| SCHEMBL8195263 | 0.73 | AKR1C1 (0.42) | AKR1C1ALDH1A1LMNAOPRM1OPRL1 | |
| SCHEMBL5180168 | 0.71 | LDHA (0.43) | AKR1C1LDHALMNAOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730292-A2 | USE OF INDANOYL AMIDE TO STIMULATE SECONDARY METABOLISM IN TAXUS SP. | Phyton Biotech, Inc. (US) | 2006-12-13 | — | — | EP | claimed |
| US-20050221456-A1 | Use of indanoyl amide to stimulate secondary metabolism in Taxus sp. | PHYTON BIOTECH, INC. (US) | 2005-10-06 | — | — | US | claimed |
| WO-2005079355-A2 | USE OF INDANOYL AMIDE TO STIMULATE SECONDARY METABOLISM IN TAXUS SP. | PHYTON BIOTECH, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20130253061-A1 | METHOD OF DROXIDOPA SYNTHESIS | CHELSEA THERAPEUTICS, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| EP-1730292-A2 | USE OF INDANOYL AMIDE TO STIMULATE SECONDARY METABOLISM IN TAXUS SP. | Phyton Biotech, Inc. (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20050221456-A1 | Use of indanoyl amide to stimulate secondary metabolism in Taxus sp. | PHYTON BIOTECH, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| WO-2005079355-A2 | USE OF INDANOYL AMIDE TO STIMULATE SECONDARY METABOLISM IN TAXUS SP. | PHYTON BIOTECH, INC. (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253061-A1 | METHOD OF DROXIDOPA SYNTHESIS | DDO, DAO, COMT | AKR1C1 3225/4885ALDH1A1 2069/4885LDHA 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.