Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL15667261 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL16291044 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28793211 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL10907398 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3417188 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1331942 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL725546 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL10896997 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL842 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL240402 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071824-A | Carbon nanotube fiber with spindle joint and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-119852382-B | Hard carbon negative electrode composite material, preparation method and application thereof | 内蒙古斯诺新材料科技有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119852382-A | Hard carbon negative electrode composite material, preparation method and application thereof | 内蒙古斯诺新材料科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119724785-A | Zinc oxide varistor and preparation method thereof | 西安西电避雷器有限责任公司 | 2025-03-28 | — | — | CN | claimed |
| US-20240191128-A1 | Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore | DORF KETAL CHEMICALS FZE (AE) | 2024-06-13 | — | — | US | claimed |
| US-20230125900-A1 | Downhole Methods | HSBC BANK MIDDLE EAST LIMITED (AE) | 2023-04-27 | — | — | US | claimed |
| CN-115917789-A | Electrodeposition of pure phase SnSb from eutectic ethaline solution for sodium ion and lithium ion battery cathodes | 科罗拉多州立大学研究基金会 | 2023-04-04 | — | — | CN | claimed |
| US-11591511-B2 | Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing and acidic composition in the wellbore | FLUID ENERGY GROUP LTD (CA) | 2023-02-28 | — | — | US | claimed |
| CN-113897601-A | Chemical silver plating solution | 深圳市虹喜科技发展有限公司 | 2022-01-07 | — | — | CN | claimed |
| US-20210230476-A1 | Novel Downhole Methods And Compositions Used in Such | HSBC BANK MIDDLE EAST LIMITED (AE) | 2021-07-29 | — | — | US | claimed |
| US-20070071887-A1 | Methods of inhibiting corrosion of a metal surface | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-29 | — | — | US | claimed |
| WO-2007034155-A1 | CORROSION INHIBITOR COMPOSITIONS AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-03-29 | — | — | WO | claimed |
| US-20070069182-A1 | Corrosion inhibitor compositions and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-29 | — | — | US | claimed |
| WO-2006117517-A2 | ACIDIC TREATMENT FLUIDS COMPRISING SCLEROGLUCAN AND/OR DIUTAN AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060247135-A1 | Acidic treatment fluids comprising scleroglucan and/or diutan and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2006-11-02 | — | — | US | claimed |
| WO-2005075707-A1 | THIOL/ALDEHYDE CORROSION INHIBITORS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2005-08-18 | — | — | WO | claimed |
| US-20050169794-A1 | Thiol / aldehyde corrosion inhibitors | HALLIBURTON ENERGY SERVICES, INC. | 2005-08-04 | — | — | US | claimed |
| US-5591381-A | REACTION OF KETONE AND ALDEHYDE WITH ACID IN THE PRESENCE OF ANTIMONY OR BISMUTH COMPOUNDS | HALLIBURTON COMPANY (US) | 1997-01-07 | — | — | US | claimed |
| US-5411670-A | Aqueous liquid carrier and combination of antimony compound activated by a specific condensation product; oil field tubing | HALLIBURTON COMPANY (US) | 1995-05-02 | — | — | US | claimed |
| EP-0593230-A1 | Metal corrosion inhibiting compositions | HALLIBURTON COMPANY (US) | 1994-04-20 | — | — | EP | claimed |