Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950137 | 0.78 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL5950481 | 0.78 | ESR1 (0.39) | ESR1 | |
| SCHEMBL2943735 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C19ESR1 | |
| SCHEMBL25489581 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2ACYP1A1CYP1B1KDM4E | |
| SCHEMBL3788801 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2ACYP1A1CYP1B1KDM4E | |
| SCHEMBL845798 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 | |
| SCHEMBL5672146 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 | |
| SCHEMBL5668026 | 0.74 | ALDH1A1 (0.48) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 | |
| 1,3,5-Trimethoxybenzene SCHEMBL27413401 | 0.73 | ALDH1A1 (0.69) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 | |
| SCHEMBL11761464 | 0.72 | ALDH1A1 (0.37) | ALDH1A1POLBKMT2ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469842-A4 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORP (US) | 2006-04-26 | — | — | EP | disclosed |
| US-20050020544-A1 | Bicyclic CB2 cannabinoid receptor ligands | PHARMOS CORPORATION | 2005-01-27 | — | — | US | disclosed |
| EP-1469842-A2 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORPORATION (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063758-A2 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORPORATION (US) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020544-A1 | Bicyclic CB2 cannabinoid receptor ligands | CNR1, CNR2, CHRNE | ALDH1A1 4401/4885POLB 2382/4885KMT2A 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.