SCHEMBL5950481

SCHEMBL5950481

CCC(O)(CC)c1cc(C(O)(CC)CC)cc(C(O)(CC)CC)c1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.39
ESR2 Q92731 5/20 0.39
AR P10275 1/20 0.36
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
CHRM3 P20309 1/20 0.31
VDR P11473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5950522 0.84 ESR1 (0.40) ESR1ESR2ARGABRA1GABRB2
SCHEMBL26357011 0.83 ACHE (0.30) ESR1ESR2
SCHEMBL23220761 0.82 HMGCR (0.33)
SCHEMBL5950461 0.81 ESR1 (0.46) ESR1ESR2ARHRH3CHRM3
SCHEMBL26357072 0.80 KDM4E (0.34)
SCHEMBL26357080 0.78
SCHEMBL5666707 0.78 ALDH1A1 (0.48) ESR1
SCHEMBL2943735 0.77 ALDH1A1 (0.44) ESR1ESR2AR
SCHEMBL24118568 0.77 KLF10 (0.41) ESR1ESR2ARGABRA1GABRB2
SCHEMBL7812830 0.75 CA12 (0.46) ESR1ESR2ARGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7005216-B2 Photo mask RENESAS TECHNOLOGY CORP. (JP) 2006-02-28 US disclosed
US-6790564-B2 FOR USE IN PRODUCING SEMICONDUCTOR INTEGRATED CIRCUIT DEVICES; EFFICIENCY RENESAS TECHNOLOGY CORPORATION (JP) 2004-09-14 US disclosed
US-20030129505-A1 Krypton fluoride laser lithography; photoresist pattern RENESAS ELECTRONICS CORPORATION (JP) 2003-07-10 US disclosed
US-20020086222-A1 Photomask and manufacturing method of an electronic device therewith RENESAS ELECTRONICS CORPORATION (JP) 2002-07-04 US disclosed