Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.55 |
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832862 | 0.84 | APP (0.57) | APPIKBKBKMT2AMEN1PGR | |
| SCHEMBL9936639 | 0.82 | APP (0.55) | APPIKBKBKMT2AMEN1PGR | |
| SCHEMBL13164261 | 0.81 | APP (0.59) | APPIKBKBKMT2AMEN1PGR | |
| SCHEMBL27811389 | 0.81 | NPC1 (0.42) | KMT2AMEN1PGRMAOANPC1 | |
| SCHEMBL14832889 | 0.78 | APP (0.50) | APPIKBKBKMT2AMEN1PGR | |
| SCHEMBL27797494 | 0.78 | IKBKB (0.40) | APPIKBKBKMT2AMEN1NPC1 | |
| SCHEMBL6812091 | 0.77 | MAPT (0.40) | IKBKBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14832261 | 0.76 | APP (0.61) | APPIKBKBKMT2AMEN1NPC1 | |
| SCHEMBL5690630 | 0.75 | APP (0.47) | APPKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9034233 | 0.74 | GSK3B (0.45) | NPC1RAB9AMAPTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098555-B | Method for synthesizing ultrashort-wavelength photochromic diarylethene compound by using imidazole-thiophene aromatic heterocycle and application of compound | 江西科技师范大学 | 2017-03-22 | — | — | CN | disclosed |
| US-8368999-B2 | Article using an optical device | GENERAL ELECTRIC COMPANY (US) | 2013-02-05 | — | — | US | disclosed |
| CN-102442999-A | Photochromic pyrimidine-thiophene mixed octafluorocyclopentene compound, synthesis method and application thereof | UNIV JIANGXI NORMAL SCI & TECH | 2012-05-09 | — | — | CN | disclosed |
| US-20120033289-A1 | ARTICLE USING AN OPTICAL DEVICE | GENERAL ELECTRIC COMPANY (US) | 2012-02-09 | — | — | US | disclosed |
| US-7692878-B2 | Optical device and method | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-20090219606-A1 | DEVICE AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090219611-A1 | DEVICE AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2009-09-03 | — | — | US | disclosed |
| EP-0717740-A1 | PHOTOCHROMIC COMPOUNDS, METHODS AND INTERMEDIATES FOR PRODUCING THEM AND THEIR USE | Ciba SC Holding AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007275-A1 | PHOTOCHROMIC COMPOUNDS, METHODS AND INTERMEDIATES FOR PRODUCING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1995-03-16 | — | — | WO | disclosed |