Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.55 |
| ▸ | IKBKB | O14920 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832889 | 0.95 | APP (0.50) | APPIKBKBSNCAKMT2AMEN1 | |
| SCHEMBL14832261 | 0.92 | APP (0.61) | APPIKBKBSNCAKMT2AMEN1 | |
| SCHEMBL14832569 | 0.88 | ALDH1A1 (0.53) | APPIKBKBSNCAKMT2AMEN1 | |
| SCHEMBL14838440 | 0.88 | APP (0.44) | APPIKBKBSNCAKMT2AMEN1 | |
| SCHEMBL14832675 | 0.88 | APP (0.44) | APPIKBKBSNCAKMT2AMEN1 | |
| SCHEMBL16011230 | 0.86 | TRPA1 (0.55) | APPSNCAKMT2AMEN1NPC1 | |
| SCHEMBL14838257 | 0.86 | TRPA1 (0.55) | APPSNCAKMT2AMEN1NPC1 | |
| SCHEMBL16011309 | 0.84 | TRPA1 (0.49) | APPIKBKBSNCANPC1RAB9A | |
| SCHEMBL14838363 | 0.84 | TRPA1 (0.49) | APPIKBKBSNCANPC1RAB9A | |
| SCHEMBL14832393 | 0.84 | OPRD1 (0.51) | APPIKBKBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690045-B | Diarylethene compounds and uses thereof | 首诺加拿大公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| EP-2652547-B1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MAT INC (CA) | 2019-10-23 | — | — | EP | disclosed |
| EP-2652547-B1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MAT INC (CA) | 2019-10-23 | — | — | EP | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | SWITCH MATERIALS, INC. (CA) | 2019-04-09 | — | — | US | disclosed |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2018-11-29 | — | — | US | disclosed |
| US-10139695-B2 | Variable transmittance optical devices | SWITCH MATERIALS, INC. (CA) | 2018-11-27 | — | — | US | disclosed |
| EP-3385354-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | Switch Materials, Inc. (CA) | 2018-10-10 | — | — | EP | disclosed |
| EP-2652547-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | Switch Materials, Inc. (CA) | 2013-10-23 | — | — | EP | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2012079159-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS INC. (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079159-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS INC. (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079160-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079160-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | APP 3371/4885IKBKB 4052/4885SNCA 3283/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | APP 3371/4885IKBKB 4052/4885SNCA 3283/4885 |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | HCN2, HCN4, HCN1 | APP 1934/4885IKBKB 3980/4885SNCA 428/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | APP 3371/4885IKBKB 4052/4885SNCA 3283/4885 |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | HCN2, KCNH2, KCNH3 | APP 3543/4885IKBKB 3230/4885SNCA 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.