Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 2/20 | 0.33 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PMM2 | O15305 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955571 | 0.88 | ALDH1A1 (0.43) | ALDH1A1EEF2KPOLBMAPTHTT | |
| SCHEMBL2950047 | 0.86 | HTR3A (0.44) | ALDH1A1KMT2AKDM4ECSF1R | |
| Ammonia Solution, Strong SCHEMBL2949465 | 0.85 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTHTTTP53 | |
| SCHEMBL1267170 | 0.85 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTHTTTP53 | |
| SCHEMBL2949772 | 0.84 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTHTTTP53 | |
| Lithium Ion SCHEMBL1267169 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTHTTTP53 | |
| SCHEMBL2951962 | 0.82 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTTP53SMN1; SMN2 | |
| SCHEMBL5667484 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5668095 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5667034 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2006-11-02 | — | — | US | claimed |
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | MAPKAPK2, MAP3K6, MAP3K12 | ALDH1A1 2307/4885CNR1 2013/4885CNR2 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.