SCHEMBL5667283

SCHEMBL5667283

CCCCC#Cc1cccc(Oc2cc(C(=O)O)ccc2C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 3/20 0.48
TTR P02766 1/20 0.43
PLA2G4B P0C869 2/20 0.40
POLB P06746 2/20 0.40
ALOX5 P09917 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CASP6 P55212 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
PTPN11 Q06124 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
MMP2 P08253 1/20 0.39
MMP12 P39900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747765 0.83 HAO1 (0.55) HAO1PLA2G4BPOLBALOX5
SCHEMBL5669480 0.82 TTR (0.52) HAO1TTRPOLBALOX5KDM4E
SCHEMBL5667377 0.80 LMNA (0.43) TTRKDM4EPTPN11
SCHEMBL5667604 0.79 PTPN11 (0.45) PTPN11MMP2MMP12
SCHEMBL5667777 0.78 HAO1 (0.49) HAO1TTRPOLBKDM4ECASP6
SCHEMBL28045609 0.75 AKR1C3 (0.64) TTRPOLBKDM4E
SCHEMBL2747372 0.74 TP53 (0.50) HAO1PLA2G4BTP53TSHRMMP2
SCHEMBL2747816 0.73 ALDH1A1 (0.46) PLA2G4BKDM4ETP53TSHRPTPN11
SCHEMBL5667405 0.73 FFAR1 (0.49) MMP2MMP12
SCHEMBL3252700 0.73 TSHR (0.50) TTRPLA2G4BTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed