SCHEMBL5667299

SCHEMBL5667299

C#Cc1ccccc1Oc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 1/20 0.44
LPAR5 Q9H1C0 1/20 0.44
EZH2 Q15910 1/20 0.44
AKR1C3 P42330 1/20 0.44
TTR P02766 2/20 0.43
MAPK14 Q16539 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.38
FABP7 O15540 1/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
SRD5A2 P31213 1/20 0.37
CTNNB1 P35222 1/20 0.36
CYP3A4 P08684 1/20 0.36
NR4A2 P43354 1/20 0.36
DAO P14920 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707884 0.96 DHODH (0.42) LPAR1LPAR5EZH2AKR1C3TTR
SCHEMBL2746171 0.93 DHODH (0.44) LPAR1LPAR5EZH2AKR1C3TTR
SCHEMBL2746893 0.82 NPC1 (0.43) LPAR1LPAR5AKR1C3TTRMAPK14
SCHEMBL6341056 0.79 MRGPRX4 (0.55) LPAR1LPAR5AKR1C3TTRMEN1
SCHEMBL5667931 0.79 FFAR1 (0.41) LPAR1LPAR5AKR1C3TTRMAPK14
SCHEMBL2745853 0.78 KDM4E (0.43) LPAR1LPAR5EZH2AKR1C3TTR
SCHEMBL2748004 0.77 GAA (0.47) EZH2KMT2APOLBGAACTNNB1
SCHEMBL28423664 0.77 HTT (0.54) AKR1C3TTRMEN1KMT2ACTNNB1
SCHEMBL6340212 0.77 TTR (0.60) AKR1C3TTRMEN1KMT2AMRGPRX4
SCHEMBL6341195 0.76 GAA (0.50) AKR1C3TTRMEN1KMT2AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed