SCHEMBL6340212

SCHEMBL6340212

O=C(O)c1cc(Oc2ccccc2O)cc(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.60
AKR1C3 P42330 1/20 0.49
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.43
AR P10275 1/20 0.42
F2 P00734 1/20 0.42
F10 P00742 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27818369 0.86 AKR1C3 (0.69) TTRAKR1C3KMT2AF2F10
SCHEMBL15010954 0.84 TTR (0.67) TTRTSHRHPGDCA1CA2
SCHEMBL28423664 0.82 HTT (0.54) TTRAKR1C3MEN1KMT2ATSHR
Benzoic Acid SCHEMBL27449817 0.81 TSHR (0.58) TTRAKR1C3MEN1KMT2ATSHR
SCHEMBL6341808 0.81 AKR1C3 (0.47) TTRAKR1C3MEN1KMT2ATSHR
SCHEMBL6343006 0.81 AKR1C3 (0.47) TTRAKR1C3MEN1KMT2ATSHR
SCHEMBL6341195 0.81 GAA (0.50) TTRAKR1C3MEN1KMT2ATSHR
SCHEMBL6341056 0.81 MRGPRX4 (0.55) TTRAKR1C3MEN1KMT2AMRGPRX4
Bicarbonate SCHEMBL6919886 0.79 TTR (0.59) TTRKMT2ATSHRHTTKDM4E
SCHEMBL1768785 0.79 AKR1C3 (0.74) TTRAKR1C3MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949674-B2 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2005-09-27 US disclosed
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-04-08 US disclosed
EP-1346975-A1 AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH SUMITOMO BAKELITE CO., LTD. (JP) 2003-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both CCR1, CCRL2, CCR6 TTR 1607/4885AKR1C3 137/4885MEN1 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.