SCHEMBL5667463

SCHEMBL5667463

O=C(O)c1ccc2c(C#Cc3ccc(-c4ccccc4)cc3)c(C(=O)O)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.48
PTPRC P08575 2/20 0.41
PTPN2 P17706 2/20 0.41
PTPN6 P29350 2/20 0.41
PTPN9 P43378 2/20 0.41
DUSP3 P51452 2/20 0.41
PTPN11 Q06124 2/20 0.41
PTPN22 Q9Y2R2 2/20 0.41
ERN1 O75460 2/20 0.41
HNF4A P41235 2/20 0.40
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
DCLRE1A Q6PJP8 1/20 0.40
DCLRE1B Q9H816 1/20 0.40
KDM4E B2RXH2 1/20 0.39
EGFR P00533 1/20 0.39
GRIN2D O15399 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2C Q14957 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5668817 0.92 PTPN1 (0.53) PTPN1PTPRCPTPN2PTPN6PTPN9
SCHEMBL5669165 0.90 PTPN1 (0.49) PTPN1PTPRCPTPN2PTPN6PTPN9
SCHEMBL5668167 0.80 PTPN1 (0.50) PTPN1PTPRCPTPN9PTPN11PTPN22
SCHEMBL5667310 0.80 PTPN1 (0.41) PTPN1ERN1CDC25BATMKDM4E
SCHEMBL27503365 0.78 HNF4A (0.46) HNF4ACDC25BATMACMSDDCLRE1A
SCHEMBL5669844 0.76 PTPN1 (0.54) PTPN1PTPRCPTPN9PTPN11PTPN22
SCHEMBL10898764 0.76 PTPN1 (0.56) PTPN1PTPN11ERN1KDM4EGRIN2D
SCHEMBL5668837 0.76 HNF4A (0.49) PTPN1PTPRCPTPN2PTPN6PTPN9
SCHEMBL9448663 0.75 PTPN1 (0.58) PTPN1ERN1HNF4ACDC25BATM
SCHEMBL5667493 0.75 PTPN1 (0.54) PTPN1PTPRCPTPN9PTPN11PTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed