SCHEMBL5669165

SCHEMBL5669165

O=C(O)c1ccc2c(C#Cc3cccc(-c4ccccc4)c3)c(C(=O)O)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.49
KMO O15229 1/20 0.43
ERN1 O75460 2/20 0.42
XDH P47989 1/20 0.40
SLC22A12 Q96S37 1/20 0.40
PTPN6 P29350 5/20 0.40
PTPN11 Q06124 5/20 0.40
PTPN22 Q9Y2R2 5/20 0.40
PTPRC P08575 4/20 0.40
PTPN2 P17706 4/20 0.40
PTPN9 P43378 4/20 0.40
DUSP3 P51452 4/20 0.40
HNF4A P41235 2/20 0.39
ACMSD Q8TDX5 1/20 0.38
DCLRE1A Q6PJP8 1/20 0.38
DCLRE1B Q9H816 1/20 0.38
EPM2A O95278 1/20 0.38
PTPRG P23470 1/20 0.38
ACP1 P24666 1/20 0.38
PTPN7 P35236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667463 0.90 PTPN1 (0.48) PTPN1KMOERN1PTPN6PTPN11
SCHEMBL5668817 0.90 PTPN1 (0.53) PTPN1PTPN6PTPN11PTPN22PTPRC
SCHEMBL5666527 0.81 KMO (0.43) PTPN1KMOERN1IP6K1IP6K3
SCHEMBL5669133 0.80 HNF4A (0.50) PTPN1KMOXDHSLC22A12PTPN6
SCHEMBL5669844 0.80 PTPN1 (0.54) PTPN1KMOERN1PTPN11PTPN22
SCHEMBL5667285 0.79 KMO (0.50) KMOXDHSLC22A12HNF4AACMSD
SCHEMBL5667919 0.75 DDT (0.49) PTPN1KMOXDHSLC22A12PTPN6
SCHEMBL5668167 0.75 PTPN1 (0.50) PTPN1ERN1SLC22A12PTPN11PTPN22
SCHEMBL10898764 0.74 PTPN1 (0.56) PTPN1ERN1PTPN11PLA2G2DKDM4E
SCHEMBL5666512 0.74 KMO (0.44) KMOXDHSLC22A12PTPRCHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed