SCHEMBL566747

SCHEMBL566747

O=C(NNc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1Cl)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.36
MEN1 O00255 5/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 8/20 0.35
MAPT P10636 7/20 0.35
HTT P42858 4/20 0.35
ALDH1A1 P00352 3/20 0.35
LMNA P02545 3/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PGR P06401 1/20 0.35
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
APAF1 O14727 2/20 0.34
NSD2 O96028 2/20 0.34
CASP3 P42574 2/20 0.34
SENP8 Q96LD8 2/20 0.34
SENP7 Q9BQF6 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10039106 0.89 MAPT (0.38) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL566693 0.88 GAA (0.36) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL566577 0.88 GAA (0.36) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL566017 0.86 GAA (0.39) KMT2AMEN1GAAMAPTHTT
SCHEMBL566034 0.83 GAA (0.40) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL472622 0.83 CA1 (0.33) KMT2AMEN1GAAMAPTHTT
SCHEMBL472295 0.83 CA1 (0.35) KMT2AMEN1GAA
SCHEMBL5008771 0.82 USP2 (0.45) KMT2AMEN1L3MBTL1MAPTALDH1A1
SCHEMBL472769 0.81 CA1 (0.34) KMT2AMEN1GAAPDK1PDK2
SCHEMBL16508607 0.81 CA1 (0.34) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2647285-A2 Pest control composition Sumitomo Chemical Company, Limited (JP) 2013-10-09 EP disclosed
US-8507514-B2 Hydrazide compound and use of the same in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-13 US disclosed
EP-2601835-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2601837-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company, Limited (JP) 2013-06-12 EP disclosed
EP-2601838-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2601836-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-06-12 EP disclosed
US-20130137682-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137682-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130131115-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131115-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131117-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131083-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131117-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131118-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131118-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131116-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131116-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20120035218-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20120035218-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130137682-A1 PEST CONTROL COMPOSITION H1-4, HRH4, CHRM2 KMT2A 992/4885MEN1 1910/4885L3MBTL1 280/4885
US-20130131115-A1 PEST CONTROL COMPOSITION HRH2, HRH4, HRH1 KMT2A 1087/4885MEN1 2036/4885L3MBTL1 723/4885
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL H1-4, H1-2, H1-0 KMT2A 420/4885MEN1 1591/4885L3MBTL1 343/4885
US-20130131118-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 KMT2A 416/4885MEN1 1259/4885L3MBTL1 82/4885
US-20130131116-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 KMT2A 531/4885MEN1 1323/4885L3MBTL1 91/4885
US-20130131083-A1 PEST CONTROL COMPOSITION H1-4, H1-3, H1-0 KMT2A 823/4885MEN1 1659/4885L3MBTL1 127/4885
US-20130131117-A1 PEST CONTROL COMPOSITION H1-4, H1-0, H1-2 KMT2A 572/4885MEN1 625/4885L3MBTL1 139/4885
US-20120035218-A1 PEST CONTROL COMPOSITION CTRL, CYP4F3, CYP4B1 KMT2A 533/4885MEN1 2851/4885L3MBTL1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.