SCHEMBL566017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL566693	0.89	GAA (0.36)	GAAPTGS2LMNAKMT2AKDM4E
	SCHEMBL10039193	0.89	NPC1 (0.39)	GAAHTTKMT2AKDM4EMAPT
	SCHEMBL566577	0.88	GAA (0.36)	GAALMNAKMT2AKDM4EMAPT
	SCHEMBL566747	0.86	KMT2A (0.36)	GAAHTTLMNAKMT2ACYP3A4
	SCHEMBL1547830	0.86	MAPT (0.43)	HTTLMNAKMT2ACYP3A4KDM4E
	SCHEMBL28908207	0.86	HTT (0.38)	PTGS2HTTLMNAKMT2ACYP3A4
	SCHEMBL472295	0.85	CA1 (0.35)	GAAKMT2ARAB9AMEN1
	SCHEMBL10132745	0.85	HTT (0.35)	GAAHTTLMNAKDM4EMAPT
	SCHEMBL472769	0.84	CA1 (0.34)	GAAKMT2ARAB9AMEN1
	SCHEMBL16508607	0.84	CA1 (0.34)	GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.