SCHEMBL5667648

SCHEMBL5667648

CC(C)(c1ccc(C#Cc2ccccc2)cc1C(=O)O)c1ccc(C#Cc2ccccc2)cc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.61
AKR1C2 P52895 1/20 0.49
AKR1C1 Q04828 1/20 0.49
RARB P10826 1/20 0.42
RARG P13631 1/20 0.42
FFAR1 O14842 8/20 0.41
DHODH Q02127 1/20 0.40
PTPN11 Q06124 1/20 0.40
FFAR4 Q5NUL3 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
APP P05067 1/20 0.39
ASIC3 Q9UHC3 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.38
GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669819 0.89 HNF4A (0.63) HNF4AAKR1C2AKR1C1RARBRARG
SCHEMBL2747049 0.81 HNF4A (0.58) HNF4AAKR1C2AKR1C1FFAR1PTPN11
SCHEMBL2746253 0.80 PTGS1 (0.37) HNF4AAKR1C2AKR1C1RARBRARG
SCHEMBL542005 0.79 HNF4A (0.73) HNF4AAKR1C2AKR1C1FFAR1DHODH
SCHEMBL14252115 0.78 HNF4A (0.67) HNF4AAKR1C2AKR1C1FFAR1DHODH
SCHEMBL5667149 0.78 HNF4A (0.71) HNF4AAKR1C2AKR1C1FFAR1PTPN11
SCHEMBL5669120 0.77 FFAR1 (0.44) FFAR1FFAR4
SCHEMBL2620526 0.77 HNF4A (0.65) HNF4AAKR1C2AKR1C1FFAR1DHODH
SCHEMBL5669586 0.76 HNF4A (0.44) HNF4AAKR1C2AKR1C1RARBRARG
SCHEMBL23143181 0.75 HNF4A (0.63) HNF4AAKR1C2AKR1C1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed