SCHEMBL5667690

SCHEMBL5667690

NNC(=O)c1csc(-c2ccc(O)cc2)n1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
ALDH1A1 P00352 2/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
POLB P06746 1/20 0.56
GAA P10253 1/20 0.55
HPGD P15428 2/20 0.54
TDP1 Q9NUW8 1/20 0.52
TLR7 Q9NYK1 5/20 0.52
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49
HPGDS O60760 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2551173 0.86 RAB9A (0.76) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2552765 0.86 GAA (0.74) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2552079 0.86 HDAC6 (0.78) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2551990 0.86 TLR7 (0.64) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2555278 0.86 HPGD (0.72) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL11511135 0.86 HDAC1 (0.74) HDAC1HDAC8HDAC6ALDH1A1GAA
Hydrazine SCHEMBL27906351 0.84 HDAC1 (0.72) HDAC1HDAC8HDAC6ALDH1A1GAA
SCHEMBL25003939 0.82 TLR7 (0.66) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2552121 0.82 TLR7 (0.66) HDAC1HDAC8HDAC6ALDH1A1RAB9A
SCHEMBL2546011 0.82 ALDH1A1 (0.73) HDAC1HDAC8HDAC6ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
EP-3494396-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF Pierce Biotechnology, Inc. (US) 2019-06-12 EP claimed
US-20180043355-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. 2018-02-15 US claimed
WO-2018027004-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. (US) 2018-02-08 WO claimed
WO-2006076034-A2 STABILIZED TWO COMPONENT SYSTEM FOR CHEMILUMIESCENT ASSAY IN IMMUNODIAGNOSTICS BHANU, KALRA (US) 2006-07-20 WO claimed
EP-1254252-A4 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ P (US) 2006-06-07 EP claimed
US-20050272108-A1 Stabilized two component system for chemiluminescent assay in immunodiagnostics KALRA BHANU 2005-12-08 US claimed
US-6602679-B2 Substrate of an oxidant, stabilizer and buffer with an extended shelf life is useful with enzyme based probes; detecting DNA fragments in DNA sequencing GIRI BRIJ (US) 2003-08-05 US claimed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US claimed
WO-2001055446-A1 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ PAL (US) 2001-08-02 WO claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP disclosed
US-10722882-B2 Chemiluminescent and fluorescent substrate pads and uses thereof PIERCE BIOTECHNOLOGY, INC. (US) 2020-07-28 US disclosed
EP-3494396-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF Pierce Biotechnology, Inc. (US) 2019-06-12 EP disclosed
US-20180043355-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. 2018-02-15 US disclosed
WO-2018027004-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. (US) 2018-02-08 WO disclosed
WO-2006076034-A2 STABILIZED TWO COMPONENT SYSTEM FOR CHEMILUMIESCENT ASSAY IN IMMUNODIAGNOSTICS BHANU, KALRA (US) 2006-07-20 WO disclosed
US-20050272108-A1 Stabilized two component system for chemiluminescent assay in immunodiagnostics KALRA BHANU 2005-12-08 US disclosed
US-6602679-B2 Substrate of an oxidant, stabilizer and buffer with an extended shelf life is useful with enzyme based probes; detecting DNA fragments in DNA sequencing GIRI BRIJ (US) 2003-08-05 US disclosed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US disclosed