Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8508484 | 0.98 | SLC6A4 (0.57) | SLC6A4SLC6A3HRH3TAAR1SLC6A2 | |
| SCHEMBL3052267 | 0.83 | HRH3 (0.59) | SLC6A4SLC6A3HRH3TAAR1AOC3 | |
| SCHEMBL2056224 | 0.81 | SLC6A4 (0.66) | SLC6A4SLC6A3HRH3TAAR1SLC6A2 | |
| SCHEMBL1971365 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL3396909 | 0.79 | SLC6A4 (0.56) | SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9062148 | 0.79 | TSHR (0.53) | SLC6A4SLC6A3TAAR1ALDH1A1TSHR | |
| SCHEMBL1687455 | 0.79 | TSHR (0.53) | SLC6A4SLC6A3ALDH1A1TSHRDAO | |
| SCHEMBL16268473 | 0.78 | SCN8A (0.54) | SLC6A4SLC6A3SLC6A2ALDH1A1TSHR | |
| SCHEMBL14376823 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A3HRH3SLC6A2TSHR | |
| SCHEMBL14350176 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A3HRH3SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730126-A1 | NOVEL BENZOXAZINONE DERIVATIVES USED AS LONG-ACTING BETAMIMETICS FOR TREATING RESPIRATORY ILLNESSES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092870-A1 | NOVEL BENZOXAZINONE DERIVATIVES USED AS LONG-ACTING BETAMIMETICS FOR TREATING RESPIRATORY ILLNESSES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-06 | — | — | WO | disclosed |
| EP-0901459-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997037967-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1997-10-16 | — | — | WO | disclosed |