Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229985 | 0.98 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28139414 | 0.98 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27461469 | 0.95 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27946170 | 0.85 | NR5A1 (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL14680082 | 0.85 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL9773153 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL9773152 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27296401 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28342871 | 0.84 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL14680110 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556733-A4 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | GENTEX CORP (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1556733-A1 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | Gentex Corporation (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004042463-A1 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | GENTEX CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |