Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4997779 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Hydrogen Sulfide SCHEMBL27726723 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Hydrochloric Acid SCHEMBL11654712 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Bromide SCHEMBL7979442 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Methane SCHEMBL29133449 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Charcoal, Activated SCHEMBL30695269 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Ammonia Solution, Strong SCHEMBL7979304 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Iodide SCHEMBL11466143 | 0.98 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Hydrochloric Acid SCHEMBL7976748 | 0.96 | TRPA1 (0.39) | TRPA1MAOBNOS3NOS2NISCH | |
| SCHEMBL1373749 | 0.92 | TRPA1 (0.37) | TRPA1MAOBNOS3NOS2NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3060 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060970-A1 | Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance | MITODICURE GMBH (DE) | 2026-03-05 | — | — | US | claimed |
| EP-4702014-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | Nurix Therapeutics, Inc. (US) | 2026-03-04 | — | — | EP | claimed |
| US-12435068-B2 | Anthelmintic compounds | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-10-07 | — | — | US | claimed |
| US-12391682-B2 | Isoquinoline derivatives and their use for the treatment of parasitic infections | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-08-19 | — | — | US | claimed |
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | claimed |
| CN-116764683-B | Preparation method and application of Co-MOF supported copper catalyst | 南开大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119823040-A | Preparation method of amido-containing 3, 4-dihydro-isoquinoline-1 (2H) -ketone derivative | 浙江理工大学嵊州创新研究院有限公司 | 2025-04-15 | — | — | CN | claimed |
| EP-4003524-B1 | ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-04-09 | — | — | EP | claimed |
| CN-119685868-A | High-activity gamma-Ni (Co) OOH catalyst, preparation method thereof and surface in-situ cleaning method | 安徽大学 | 2025-03-25 | — | — | CN | claimed |
| EP-3634959-B1 | QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-02-26 | — | — | EP | claimed |
| WO-1988000586-A1 | PROCESS FOR THE PREPARATION OF 3,4-DIHYDROISOQUINOLINE | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-01-28 | — | — | WO | claimed |
| US-4717724-A | FUNGICIDES, ANTIPROTOZOA, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-05 | — | — | US | claimed |
| US-4678792-A | ANTITHROMBIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1987-07-07 | — | — | US | claimed |
| EP-0028959-B1 | 5,8,13,13A-TETRAHYDRO-6H-DIBENZO(A,G)QUINOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | U.R.P.H.A. (FR) | 1985-01-30 | — | — | EP | claimed |
| EP-0028959-A1 | 5,8,13,13a-Tetrahydro-6H-dibenzo(a,g)quinolizine derivatives, process for their preparation and pharmaceutical compositions containing them | U.R.P.H.A. (FR) | 1981-05-20 | — | — | EP | claimed |
| EP-0009174-A1 | Novel (5-(3,4-dihydroisoquinolin-1-yl)-1H-benzimidazol-2-yl)-carbamic acid alkylesters, processes for the production thereof, medicaments based on said compounds and process for the production of anthelmintic agents | BAYER AG (DE) | 1980-04-02 | — | — | EP | claimed |
| US-4118494-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | claimed |
| US-4014884-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | claimed |
| US-3983122-A | FROM CYCLOALKENYL KETONE AND DIHYDROISOQUINOLINE, ANTIDEPRESSANT | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | claimed |
| US-3970461-A | Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |