Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7976748 | 0.98 | TRPA1 (0.39) | TRPA1MAOBNOS3NOS2NISCH | |
| SCHEMBL56690 | 0.98 | TRPA1 (0.42) | TRPA1MAOBNOS3NOS2NISCH | |
| Hydrogen Sulfide SCHEMBL27726723 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Bromide SCHEMBL7979442 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Iodide SCHEMBL11466143 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Hydrochloric Acid SCHEMBL11654712 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Charcoal, Activated SCHEMBL30695269 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| SCHEMBL4997779 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| Methane SCHEMBL29133449 | 0.95 | TRPA1 (0.41) | TRPA1MAOBNOS3NOS2NISCH | |
| SCHEMBL1373749 | 0.90 | TRPA1 (0.37) | TRPA1MAOBNOS3NOS2NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087843-A1 | COMPOUNDS FOR TREATING DISORDERS WHERE A DECREASED LEVEL OF PLASMA FFA IS DESIRED | NOVO NORDISK A/S (DK) | 2001-11-22 | — | — | WO | disclosed |