SCHEMBL5669353

SCHEMBL5669353

CC(C)(C)OOOC(=O)CCCCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
LMNA P02545 2/20 0.42
NFKB1 P19838 1/20 0.41
PMP22 Q01453 1/20 0.41
AKR1B1 P15121 1/20 0.40
ALDH1A1 P00352 3/20 0.39
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 7/20 0.39
PPARD Q03181 7/20 0.39
PPARA Q07869 7/20 0.39
HDAC11 Q96DB2 5/20 0.39
PTPN1 P18031 3/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
SLC22A6 Q4U2R8 2/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491917 0.98 TSHR (0.44) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL27585068 0.96 TSHR (0.50) TSHRLMNANFKB1PMP22AKR1B1
SCHEMBL1845580 0.92 TSHR (0.37) TSHRLMNAALDH1A1TDP1ALOX15
SCHEMBL491916 0.90 DGKA (0.38) TSHRLMNAALDH1A1TDP1ALOX15
SCHEMBL679714 0.90 DGKA (0.38) TSHRLMNAALDH1A1TDP1ALOX15
SCHEMBL2027985 0.88 EGLN1 (0.42) TSHRLMNAALDH1A1TDP1ESR1
SCHEMBL28009532 0.88 TSHR (0.48) TSHRLMNANFKB1PMP22AKR1B1
SCHEMBL8031597 0.88 TSHR (0.42) TSHRALDH1A1TDP1HSD17B10
SCHEMBL28459852 0.86 TSHR (0.48) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL23819 0.85 DGKA (0.47) TSHRLMNAAKR1B1ALDH1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114426669-A Modified sepiolite fiber and graft copolymer thereof, tetrapropylene fluoride rubber sizing material, sealing rubber ring, and preparation method and application thereof 中国石油化工股份有限公司 2022-05-03 CN claimed
CN-116710513-A Fluororubber composition and sealing material NOK株式会社 2023-09-05 CN disclosed
CN-112026308-B Stretchable structure, multilayer stretchable sheet, woven yarn, and fiber structure 三井化学株式会社 2022-09-06 CN disclosed
CN-114426669-A Modified sepiolite fiber and graft copolymer thereof, tetrapropylene fluoride rubber sizing material, sealing rubber ring, and preparation method and application thereof 中国石油化工股份有限公司 2022-05-03 CN disclosed
WO-2021065199-A1 FLUORORUBBER COMPOSITION AND SEAL MATERIAL ユニマテック株式会社 2021-04-08 WO disclosed
CN-112026308-A Stretchable structure, multilayer stretchable sheet, woven yarn, and fiber structure 三井化学株式会社 2020-12-04 CN disclosed
EP-0658943-B1 SOLAR CELL MODULE HAVING EXCELLENT WEATHER RESISTANCE CANON KK (JP) 2006-08-30 EP disclosed
US-5718772-A FILLER IS MADE OF VINYLIDENE FLUORIDE COPOLYMER AND ACRYLIC RESIN; EXCELLENT HEAT/WEAR RESISTANCE; DESIRABLE PHOTOELECTRIC CONVERSION EFFICIENCY OVER A LONG PERIOD OF TIME CANON KABUSHIKI KAISHA (JP) 1998-02-17 US disclosed
US-5578141-A Solar cell module having excellent weather resistance CANON KABUSHIKI KAISHA (JP) 1996-11-26 US disclosed
EP-0658943-A1 SOLAR CELL MODULE HAVING EXCELLENT WEATHER RESISTANCE CANON KABUSHIKI KAISHA (JP) 1995-06-21 EP disclosed