SCHEMBL8031597

SCHEMBL8031597

CC(C)(C)OOOC(=O)CCCC(=O)OOOC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DGKA P23743 1/20 0.30
RECQL P46063 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1845580 0.95 TSHR (0.37) TSHRTDP1ALDH1A1HSD17B10DGKA
SCHEMBL491916 0.93 DGKA (0.38) TSHRTDP1ALDH1A1HSD17B10DGKA
SCHEMBL679714 0.93 DGKA (0.38) TSHRTDP1ALDH1A1HSD17B10DGKA
SCHEMBL27585068 0.92 TSHR (0.50) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL8032017 0.91 TSHR (0.38) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL1070030 0.90 DGKA (0.39) TSHRALDH1A1DGKARECQL
SCHEMBL23819 0.88 DGKA (0.47) TSHRALDH1A1DGKA
SCHEMBL5669353 0.88 TSHR (0.45) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL28623285 0.88 TSHR (0.32) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL491917 0.86 TSHR (0.44) TSHRTDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000068192-A2 PROCESS FOR THE PREPARATION OF (DI)ALKYLPEROXY ESTERS OF (DI)CARBOXYLIC ACIDS AKZO NOBEL N.V. (NL) 2000-11-16 WO disclosed