Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105950 | 0.75 | — | — | |
| SCHEMBL109960 | 0.71 | TSHR (0.41) | TDP1ALDH1A1FFAR3LMNATSHR | |
| SCHEMBL20314923 | 0.71 | — | — | |
| SCHEMBL29296412 | 0.69 | GRIK1 (0.39) | TDP1ALDH1A1FFAR3 | |
| SCHEMBL26735528 | 0.69 | TDP1 (0.32) | TDP1ALDH1A1FFAR3 | |
| SCHEMBL11273705 | 0.67 | TDP1 (0.36) | TDP1ALDH1A1FFAR3TSHR | |
| SCHEMBL11273704 | 0.67 | TDP1 (0.36) | TDP1ALDH1A1FFAR3TSHR | |
| SCHEMBL43655 | 0.67 | — | — | |
| SCHEMBL7752906 | 0.67 | ALDH1A1 (0.41) | TDP1ALDH1A1FFAR3TSHR | |
| SCHEMBL2784326 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551418-A4 | SUBSTITUTED KETOPHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RES SARL (CH) | 2006-05-03 | — | — | EP | disclosed |
| EP-1551418-A1 | SUBSTITUTED KETOPHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | Ilex Oncology Research Sàrl (CH) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004026315-A1 | SUBSTITUTED KETOPHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| WO-2004026242-A2 | SUBSTITUTED KETOPHOSPHONATE INHIBITORS OF TUMOR CELL PROLIFERATION | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |