SCHEMBL5669459

SCHEMBL5669459

O=P(O)(O)OC1COO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320444 0.79
SCHEMBL30223384 0.70 INPP5A (0.36)
SCHEMBL29167358 0.70
SCHEMBL27449793 0.69 SMPD1 (0.33)
SCHEMBL28290241 0.67 SMPD1 (0.32)
SCHEMBL28170980 0.67 SMPD1 (0.32)
SCHEMBL9571898 0.67 INPP5A (0.45)
SCHEMBL6690286 0.65 INPP5A (0.35)
Phosphoric Acid SCHEMBL11760570 0.65 CA2 (0.32)
SCHEMBL26919943 0.64 INPP5A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629195-B1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX INC (US) 1999-05-26 EP claimed
EP-0629195-A4 1995-01-11 EP claimed
EP-0629195-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1994-12-21 EP claimed
WO-1993018022-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1993-09-16 WO claimed
EP-3465847-A1 SYSTEM AND METHOD FOR MICRO LASER PARTICLES The General Hospital Corporation (US) 2019-04-10 EP disclosed
US-20060079699-A1 Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates APPLIED BIOSYSTEMS, LLC 2006-04-13 US disclosed
EP-0629195-B1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX INC (US) 1999-05-26 EP disclosed
EP-0629195-B1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX INC (US) 1999-05-26 EP disclosed
EP-0497972-B1 CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES TROPIX INC (US) 1998-12-23 EP disclosed
US-5831102-A HEAT RESISTANCE; STABILITY TROPIX, INC. (US) 1998-11-03 US disclosed
US-5756770-A Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1998-05-26 US disclosed
US-5756770-A Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1998-05-26 US disclosed
US-5330900-A Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes TROPIX, INC. (US) 1994-07-19 US disclosed
US-5326882-A High speed bioassay TROPIX, INC. (US) 1994-07-05 US disclosed
US-5306621-A Enhanced chemiluminescent assay BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-04-26 US disclosed
WO-1993018022-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1993-09-16 WO disclosed
WO-1993018022-A1 SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR TROPIX, INC. (US) 1993-09-16 WO disclosed
EP-0497972-A1 CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES TROPIX, INC. (US) 1992-08-12 EP disclosed
US-5112960-A Enzyme cleavable 1,2-dioxetane compound APPLIED BIOSYSTEMS, LLC 1992-05-12 US disclosed
WO-1992004341-A1 CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES TROPIX, INC. (US) 1992-03-19 WO disclosed