Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4260895 | 1.00 | MCHR1 (0.41) | MCHR1ADRA2AADRA1AHRH1CXCR3 | |
| SCHEMBL4265059 | 0.94 | MCHR1 (0.45) | MCHR1ADRA2AADRA1AHRH1CXCR3 | |
| SCHEMBL4265061 | 0.94 | MCHR1 (0.45) | MCHR1ADRA2AADRA1AHRH1CXCR3 | |
| Trifluoroacetic Acid SCHEMBL4265548 | 0.87 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL4257937 | 0.83 | NPC1 (0.52) | MCHR1CXCR3NPC1RAB9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL4262987 | 0.81 | MCHR1 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL4262982 | 0.81 | MCHR1 (0.47) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL4262855 | 0.80 | MCHR1 (0.57) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL4262853 | 0.80 | MCHR1 (0.57) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL4258666 | 0.79 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730122-A2 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005095357-A2 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-13 | — | — | WO | disclosed |