Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | PTEN | P60484 | 1/20 | 0.48 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298669 | 0.88 | KEAP1 (0.52) | KEAP1FFAR1NPSR1PTPRBCDC25A | |
| SCHEMBL7076068 | 0.88 | KEAP1 (0.52) | KEAP1FFAR1NPSR1PTPRBCDC25A | |
| SCHEMBL70271 | 0.85 | KEAP1 (0.74) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL490382 | 0.85 | KEAP1 (0.54) | KEAP1FFAR1NPSR1PTPRBCDC25A | |
| SCHEMBL5846204 | 0.83 | FFAR1 (0.61) | KEAP1FFAR1NPSR1FFAR4THRA | |
| Hydrochloric Acid SCHEMBL10982620 | 0.83 | KEAP1 (0.71) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL1249170 | 0.83 | KEAP1 (0.52) | KEAP1FFAR1NPSR1FFAR4THRA | |
| SCHEMBL1448093 | 0.83 | KEAP1 (0.52) | KEAP1FFAR1NPSR1PTPRBCDC25A | |
| SCHEMBL17672986 | 0.83 | KEAP1 (0.52) | KEAP1FFAR1NPSR1FFAR4THRA | |
| SCHEMBL31245820 | 0.83 | KEAP1 (0.52) | KEAP1FFAR1NPSR1PTPRBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084419-B2 | Pharmaceutical compositions for sustained drug delivery | GlaxoSmithKline, LLC (US) | 2011-12-27 | — | — | US | disclosed |
| US-20060094662-A1 | Pharmaceutical compositions for sustained drug delivery | GLAXOSMITHKLINE LLC | 2006-05-04 | — | — | US | disclosed |
| US-7037889-B2 | Pharmaceutical compositions for sustained drug delivery | PRAECIS PHARMACEUTICALS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| EP-1320387-A2 | PHARMACEUTICAL COMPOSITIONS FOR SUSTAINED DRUG DELIVERY | Praecis Pharmaceuticals Inc. (US) | 2003-06-25 | — | — | EP | disclosed |
| US-20020086829-A1 | Pharmaceutical compositions for sustained drug delivery | PRAECIS PHARMACEUTICALS INC. | 2002-07-04 | — | — | US | disclosed |
| WO-2002022154-A2 | PHARMACEUTICAL COMPOSITIONS FOR SUSTAINED DRUG DELIVERY | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2002-03-21 | — | — | WO | disclosed |