Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670228 | 0.85 | LNPEP (0.46) | LNPEPTMEM97SIGMAR1PRMT1GRM5 | |
| SCHEMBL5670085 | 0.82 | TMEM97 (0.56) | TMEM97SIGMAR1HRH3CHRM4HTR1A | |
| SCHEMBL5165139 | 0.79 | GRIN1 (0.54) | GHSRHRH3 | |
| SCHEMBL5669989 | 0.77 | ESR1 (0.38) | SMN1; SMN2HTR1AADRA2AHTR2AHTR2B | |
| SCHEMBL10236206 | 0.76 | LNPEP (0.54) | LNPEPTMEM97SIGMAR1PRMT1GRM5 | |
| SCHEMBL14441055 | 0.76 | TMEM97 (0.48) | LNPEPTMEM97SIGMAR1PRMT1GRM5 | |
| SCHEMBL8315932 | 0.75 | MEN1 (0.57) | LNPEPPRMT1GRM5NPC1RAB9A | |
| SCHEMBL2124647 | 0.75 | ESR1 (0.44) | SIGMAR1GRM5HTR1AADRA2AHTR2B | |
| SCHEMBL5455714 | 0.74 | NAMPT (0.53) | LNPEPTMEM97SIGMAR1GRM5HRH3 | |
| SCHEMBL749352 | 0.74 | GRM5 (0.54) | LNPEPPRMT1GRM5PTGDR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730114-A1 | BENZAZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005087746-A1 | BENZAZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | WO | disclosed |